Other than Diablo 3 and FF13.
1. Darksiders (PS3)
2. Dragon Age: Origins (PC) - game was first announced 4 years back. When it gets released, it's bound to be something big.
3. Spore (PC, DS)
4. Resident Evil 5
5. SimCity Creator (Wii and DS) - I hope they allow more than just one save files this time.
6. Castlevania Order of Ecclesia (DS)
7. Valkyrie Chronicles (PS3)